Publications

2006

• Siddiqui, K. S., Poljak, A., Guilhaus, M., De Francisci, D., Curmi, P. M., Feller, G., D'Amico, S., Gerday, C., Uversky, V. N. & Cavicchioli, R. (2006). Role of lysine versus arginine in enzyme cold-adaptation: modifying lysine to homo-arginine stabilizes the cold-adapted alpha-amylase from Pseudoalteramonas haloplanktis. Proteins 64, 486-501.
• Pirani, A., Vinogradova, M. V., Curmi, P. M., King, W. A., Fletterick, R. J., Craig, R., Tobacman, L. S., Xu, C., Hatch, V. & Lehman, W. (2006). An atomic model of the thin filament in the relaxed and Ca2+-activated states. J Mol Biol 357, 707-17.

2005

• Saunders, N. F., Goodchild, A., Raftery, M., Guilhaus, M., Curmi, P. M. & Cavicchioli, R. (2005). Predicted roles for hypothetical proteins in the low-temperature expressed proteome of the Antarctic archaeon Methanococcoides burtonii. J Proteome Res 4, 464-72.
• Robinson, A., Wu, P. S., Harrop, S. J., Schaeffer, P. M., Dosztanyi, Z., Gillings, M. R., Holmes, A. J., Nevalainen, K. M., Stokes, H. W., Otting, G., Dixon, N. E., Curmi, P. M. & Mabbutt, B. C. (2005). Integron-associated mobile gene cassettes code for folded proteins: the structure of Bal32a, a new member of the adaptable alpha+beta barrel family. J Mol Biol 346, 1229-41.
• Littler, D. R., Assaad, N. N., Harrop, S. J., Brown, L. J., Pankhurst, G. J., Luciani, P., Aguilar, M. I., Mazzanti, M., Berryman, M. A., Breit, S. N. & Curmi, P. M. (2005). Crystal structure of the soluble form of the redox-regulated chloride ion channel protein CLIC4. Febs J 272, 4996-5007.
• King, W. A., Stone, D. B., Timmins, P. A., Narayanan, T., von Brasch, A. A., Mendelson, R. A. & Curmi, P. M. (2005). Solution structure of the chicken skeletal muscle troponin complex via small-angle neutron and X-ray scattering. J Mol Biol 345, 797-815.
• Doust, A. B., van Stokkum, I. H., Larsen, D. S., Wilk, K. E., Curmi, P. M., van Grondelle, R. & Scholes, G. D. (2005). Mediation of ultrafast light-harvesting by a central dimer in phycoerythrin 545 studied by transient absorption and global analysis. J Phys Chem B Condens Matter Mater Surf Interfaces Biophys 109, 14219-26.
• Di Giusto, D. A., Sutherland, A. P., Jankova, L., Harrop, S. J., Curmi, P. M. & King, G. C. (2005). Plasminogen activator inhibitor-2 is highly tolerant to P8 residue substitution--implications for serpin mechanistic model and prediction of nsSNP activities. J Mol Biol 353, 1069-80.

2004

• Saunders, N. F., Curmi, P. M. & Cavicchioli, R. (2004). An online database for the detection of novel archaeal sequences in human ESTs. Bioinformatics 20, 2361-2.
• Roberts, T. H., Hejgaard, J., Saunders, N. F., Cavicchioli, R. & Curmi, P. M. (2004). Serpins in unicellular Eukarya, Archaea, and Bacteria: sequence analysis and evolution. J Mol Evol 59, 437-47.
• Oakley, C. E., Hambly, B. D., Curmi, P. M. & Brown, L. J. (2004). Myosin binding protein C: structural abnormalities in familial hypertrophic cardiomyopathy. Cell Res 14, 95-110.
• Novarino, G., Fabrizi, C., Tonini, R., Denti, M. A., Malchiodi-Albedi, F., Lauro, G. M., Sacchetti, B., Paradisi, S., Ferroni, A., Curmi, P. M., Breit, S. N. & Mazzanti, M. (2004). Involvement of the intracellular ion channel CLIC1 in microglia-mediated beta-amyloid-induced neurotoxicity. J Neurosci 24, 5322-30.
• Littler, D. R., Harrop, S. J., Fairlie, W. D., Brown, L. J., Pankhurst, G. J., Pankhurst, S., DeMaere, M. Z., Campbell, T. J., Bauskin, A. R., Tonini, R., Mazzanti, M., Breit, S. N. & Curmi, P. M. (2004). The intracellular chloride ion channel protein CLIC1 undergoes a redox-controlled structural transition. J Biol Chem 279, 9298-305.
• Goodchild, A., Saunders, N. F., Ertan, H., Raftery, M., Guilhaus, M., Curmi, P. M. & Cavicchioli, R. (2004). A proteomic determination of cold adaptation in the Antarctic archaeon, Methanococcoides burtonii. Mol Microbiol 53, 309-21.
• Doust, A. B., Marai, C. N., Harrop, S. J., Wilk, K. E., Curmi, P. M. & Scholes, G. D. (2004). Developing a structure-function model for the cryptophyte phycoerythrin 545 using ultrahigh resolution crystallography and ultrafast laser spectroscopy. J Mol Biol 344, 135-53.

2003

• Saunders, N. F., Thomas, T., Curmi, P. M., Mattick, J. S., Kuczek, E., Slade, R., Davis, J., Franzmann, P. D., Boone, D., Rusterholtz, K., Feldman, R., Gates, C., Bench, S., Sowers, K., Kadner, K., Aerts, A., Dehal, P., Detter, C., Glavina, T., Lucas, S., Richardson, P., Larimer, F., Hauser, L., Land, M. & Cavicchioli, R. (2003). Mechanisms of thermal adaptation revealed from the genomes of the Antarctic Archaea Methanogenium frigidum and Methanococcoides burtonii. Genome Res 13, 1580-8.
• Collins, B. M., Cubeddu, L., Naidoo, N., Harrop, S. J., Kornfeld, G. D., Dawes, I. W., Curmi, P. M. & Mabbutt, B. C. (2003). Homomeric ring assemblies of eukaryotic Sm proteins have affinity for both RNA and DNA. Crystal structure of an oligomeric complex of yeast SmF. J Biol Chem 278, 17291-8.
• Cavicchioli, R., Curmi, P. M., Saunders, N. & Thomas, T. (2003). Pathogenic archaea: do they exist? Bioessays 25, 1119-28.

2002

• Williams, N. K., Prosselkov, P., Liepinsh, E., Line, I., Sharipo, A., Littler, D. R., Curmi, P. M., Otting, G. & Dixon, N. E. (2002). In vivo protein cyclization promoted by a circularly permuted Synechocystis sp. PCC6803 DnaB mini-intein. J Biol Chem 277, 7790-8.
• Warton, K., Tonini, R., Fairlie, W. D., Matthews, J. M., Valenzuela, S. M., Qiu, M. R., Wu, W. M., Pankhurst, S., Bauskin, A. R., Harrop, S. J., Campbell, T. J., Curmi, P. M., Breit, S. N. & Mazzanti, M. (2002). Recombinant CLIC1 (NCC27) assembles in lipid bilayers via a pH-dependent two-state process to form chloride ion channels with identical characteristics to those observed in Chinese hamster ovary cells expressing CLIC1. J Biol Chem 277, 26003-11.
• Ho, B. K. & Curmi, P. M. (2002). Twist and shear in beta-sheets and beta-ribbons. J Mol Biol 317, 291-308.

 

Prior 2002

• Interaction between the P14 residue and strand 2 of beta-sheet B is critical for reactive center loop insertion in Plasminogen Activator inhibitor-2
  Darren N. Saunders, Lucy Jankova, Stephen J. Harrop, Paul M. G. Curmi, Alison R. Gould, Marie Ranson, and Mark S. Baker
  J. Biol. Chem. published September 12, 2001 as 10.1074/jbc.M103123200

• Crystal structure of the soluble form of the intracellular chloride Ion channel CLIC1 (NCC27) at 1.4Å resolution
  Stephen J. Harrop, Matthew Z. DeMaere, W. Douglas Fairlie, Tamara Reztsova, Stella M. Valenzuela, Michele Mazzanti, Raffaella Tonini, Min Ru Qiu, Lucy Jankova, Kristina Warton, Asne R. Bauskin, Wan Man Wu, Susan Pankhurst, Terence J. Campbell, Samuel N. Breit, and Paul M. Curmi
  J. Biol. Chem. published September 10, 2001 as 10.1074/jbc.M107804200
• Crystal structure of the complex of plasminogen activator inhibitor 2 with a peptide mimicking the reactive center loop
  Lucy Jankova, Stephen J. Harrop, Darren N. Saunders, John L. Andrews, Kenneth C. Bertram, Alison R. Gould, Mark S. Baker, and Paul M.G. Curmi
  J. Biol. Chem. published August 23, 2001 as 10.1074/jbc.M103021200
• Crystal structure of a heptameric Sm-like protein complex from archaea: Implications for the structure and evolution of snRNPs
  Collins BM, Harrop SJ, Kornfeld GD, Dawes IW, Curmi PIG, Mabbutt BC
  J. Mol. Biol. 309(4):915-923 (2001)
• Cold stress response in Archaea
  Cavicchioli R, Thomas T, Curmi PMG
  Extremophiles 4(6): 321-331 DEC 2000
• Biased Monte Carlo optimization of protein sequences
  Cootes AP, Curmi PMG, Torda AE
  J. Chem. Phys. 113(6): 2489-2496 AUG 8 2000
• The Transition between the Open and Closed States of Rubisco is Triggered by the Inter-Phosphate Distance of the Bound Bisphosphate.
  Duff AP, Andrews TJ, Curmi PM.
  J Mol. Biol. 298(5):903-916. (2000)
• The Crystal Structure Of Plasminogen Activator Inhibitor-2 At 2. 0 A Resolution: Implications For Serpin Function.
  S. J. Harrop, L. Jankova, M. Coles, D. Jardine, J. S. Whittaker, A. R. Gould, A. Meister, G. C. King, B. C. Mabbutt, P. M. G. Curmi.
  Structure Fold Des 7:43. (1999)
• Evolution Of A Light-Harvesting Protein By Addition Of New Subunits And Rearrangement Of Conserved Elements: Crystal Structure Of A Cryptophyte Phycoerythrin At 1. 63 A Resolution.
  K. E. Wilk, S. J. Harrop, L. Jankova, D. Edler, G. Keenan, F. Sharples, R. G. Hiller, P. M. G. Curmi.
  Proc. Nat. Acad. Sci. Usa 96:8901.(1999)
• Computational studies on mutant protein stability: The correlation between surface thermal expansion and protein stability.
  R. Palma, P. M. G. Curmi.
  Protein Science 8:913-920. (1999)
• The dependence of amino acid pair correlations on structural environment.
  Adrian P. Cootes, Paul M.G. Curmi, Ross Cunningham, Christine Donnelly, Andrew E. Torda.
  Proteins: Structure, Function, and Genetics 32(2):175-189.(1998)
• An analysis of side chain interactions and pair correlations within antiparallel beta-sheets: the differences between backbone hydrogen-bonded and non-hydrogen-bonded residue pairs.
  Wouters MA, Curmi PM.
  Proteins. 22(2):119-31.(1995)